What We Study
The Chen Lab studies how disruptions in RNA regulation drive childhood cancer. Our work focuses on understanding how defects in RNA synthesis, processing, and degradation reshape gene expression programs in pediatric tumors.
Research areas
Wilms tumor
Defining how transcriptional and chromatin dysregulation contribute to pediatric kidney cancer.
Pineoblastoma
Investigating how tumors evade transcriptional inhibition and develop resistance to therapy.